TISSUE GRAFTS MODIFIED WITH A CROSS-LINKING AGENT AND METHOD OF MAKING AND USING THE SAME

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United States of America Patent

SERIAL NO

13984842

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Abstract

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Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. Also described herein are methods for making and using the tissue grafts.

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Patent Owner(s)

Patent OwnerAddress
MIMEDX GROUP INC1775 WEST OAK COMMONS CT NE MARIETTA GA 30062

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daniel, John Marietta, US 86 3225
Morse, Brenda S Marietta, US 19 957
Sith, Somaly Marietta, US 23 483
Spencer, Randall Marietta, US 50 1787

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