PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENCILLIN G ACYLASE

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United States of America Patent

APP PUB NO 20140200342A1
SERIAL NO

14128736

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a process for the preparation of 3′-thiosubstituted cephalosporins by enzymatic condensation of a nucleus with a phenylglycine derivative. Furthermore the present invention relates to a crystalline form of a compound of general formula (1) wherein R2 is OH and X is S and R1 is a radical of formula (2a) with R3 is CH3.

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Patent Owner(s)

Patent OwnerAddress
DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B VALEXANDER FLEMINGLAAN 1 DELFT 2613 AX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cusan, Claudia Echt, NL 6 0
Ijpeij, Gerard Echt, NL 1 0
Moody, Harold Echt, NL 1 0

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