BENZENESULFONAMIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR

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United States of America Patent

SERIAL NO

14096565

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Abstract

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The invention formula R1 is selected from the group consisting of hydrogen, linear C1-C3 alkyl and fluorinated linear C1-C3 alkyl; R2 is hydrogen or methyl; R is selected from the group consisting of hydrogen, halogen, C1-C2-alkyl, fluorinated C1-C2-alkyl, C1-C2-alkoxy and fluorinated C1-C2-alkoxy, R4 is C1-C2-alkyl or fluorinated C1-C2-alkyl; n is 0, 1 or 2, and the physiologically tolerated salts of these compounds and the N-oxides thereof. The invention also relates to a pharmaceutical composition that comprises at least one compound of the formula I and/or at least one physiologically tolerated acid addition salt thereof, and further to a method for treating disorders that respond beneficially to dopamine D3 receptor antagonists or dopamine D3 agonists, said method comprising administering an effective amount of at least one compound or physiologically tolerated acid addition salt of the formula I to a subject in need thereof.

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Patent Owner(s)

Patent OwnerAddress
ABBVIE DEUTSCHLAND GMBH & CO KGMAX-PLANCK-RING 2A WIESBADEN 65205

International Classification(s)

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  • 2013 Application Filing Year
  • C07D Class
  • 4936 Applications Filed
  • 4309 Patents Issued To-Date
  • 87.30 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20132014201520162017201820192020202120220255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bespalov, Anton WIESBADEN, DE 18 63
Braje, Wilfried WIESBADEN, DE 95 431
Drescher, Karla WIESBADEN, DE 77 265
Haupt, Andreas WIESBADEN, DE 99 682
Jongen-Relo, Ana Lucia WIESBADEN, DE 6 2
Lange, Udo WIESBADEN, DE 65 758
Turner, Sean Colm WIESBADEN, DE 31 107
Unger, Liliane WIESBADEN, DE 152 870

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  • C07D Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges8331701255833610822501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90100 +0100200300400500600700800900100011001200130014001500160017001800

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