POLYISOPRENYLATED TETRACYCLIC XANTHONE WITH ANTICANCER ACTIVITY

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United States of America Patent

APP PUB NO 20140194498A1
SERIAL NO

14149819

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A novel polyisoprenylated tetracyclic xanthone, named garciesculentone B, isolated from Garcinia esculenta Y. H. Li is disclosed in the present invention. This compound is shown to have significant cytotoxicity against various cancer cells. In addition, garciesculentone B is shown to have antimigration effect on various cancer cells such as human esophageal carcinoma cell. The experimental data supports that this compound is useful for developing into an anticancer drug.

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Patent Owner(s)

Patent OwnerAddress
HONG KONG BAPTIST UNIVERSITYKOWLOON TONG KOWLOON HONG KONG

International Classification(s)

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  • 2014 Application Filing Year
  • C07D Class
  • 5203 Applications Filed
  • 4627 Patents Issued To-Date
  • 88.93 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BIAN, Zhaoxiang Hong Kong, HK 41 7
CHAN, Albert Sun Chi Hong Kong, HK 20 12
CHEN, Kaixian Hong Kong, HK 52 28
CHEN, Shilin Hong Kong, HK 150 1315
LU, Aiping Hong Kong, HK 27 7
TAN, Hongsheng Hong Kong, HK 8 1
XI, Zhichao Hong Kong, HK 2 0
XU, Hongxi Hong Kong, HK 22 4
YANG, Dajian Hong Kong, HK 26 4
ZHANG, Hong Hong Kong, HK 882 11808

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  • C07D Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges8331701255833610822501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90100 +0100200300400500600700800900100011001200130014001500160017001800

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