AGROCYBE AEGERITA LECTIN AAL-2, AND ENCODING GENE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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United States of America Patent
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Issued Date -
Jul 10, 2014
app pub date -
Oct 24, 2011
filing date -
Aug 1, 2011
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Abandoned
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Abstract
The isolated Agrocybe aegerita lectin AAL-2 is able to inhibit the growth of tumor cells by inducing apoptosis. In the animal study, the Agrocybe aegerita lectin AAL-2 has been showed to be capable for tumor therapy. Furthermore, the AAL-2 preferentially binds to the carbohydrate or glycoproteins with its N-Acetylglucosamine, which can be used for diagnosing the N-Acetylglucosamine-associated diseases or detecting N-Acetylglucosamine-modified carbohydrates.
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