METHODS AND COMPOSITIONS FOR MODULATION OF AMPLIFICATION EFFICIENCY

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United States of America Patent

APP PUB NO 20140193819A1
SERIAL NO

14205229

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are methods and kits for modulating the amplification efficiency of nucleic acids, which are useful in multiplex reactions where the amplification efficiency of one or more nucleic acids in the mixture are desired to be modulated relative to one or more other nucleic acids. Embodiments relate to molecular diagnostics, including detecting sequence variants, such as SNPs, insertions deletions, and altered methylation patterns, as well as the modulation of the amplification efficiency of internal control sequences to provide more accurate control sequences for amplification reactions.

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Patent Owner(s)

Patent OwnerAddress
BECTON DICKINSON AND COMPANYFRANKLIN LAKES NJ

International Classification(s)

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  • 2014 Application Filing Year
  • C12Q Class
  • 3114 Applications Filed
  • 2141 Patents Issued To-Date
  • 68.76 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hellyer, Tobin Westminster, US 12 129
Nadeau, James G Ellicott City, US 54 2227

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  • 1 Citation Count
  • C12Q Class
  • 20.93 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges4351109245109624427148841301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +05010015020025030035040045050055060065070075080085090095010001050110011501200

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