Systems and Methods for Continuous Flow PCR Systems

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United States of America Patent

APP PUB NO 20140193800A1
SERIAL NO

14110667

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A liquid handling system of a PCR system is instructed to obtain a matrix of samples and reagents for a PCR experiment. A fluid pumping system of the PCR system is instructed to maintain a continuous flow of a transport fluid through a plurality of micro-channels that allows the mixture of the samples and the reagents producing a plurality of mixed sample droplets. One or more post-bridge detection values are received from a post-bridge detection system of the PCR system for each mixed sample droplet to determine if the mixed sample droplet is mixed correctly. A thermocycler of the PCR system is instructed to maintain one or more temperatures for cycling the temperature of the plurality of mixed sample droplets. One or more endpoint detection values are received from an endpoint detection system of the PCR system for each mixed sample droplet to analyze the PCR experiment.

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Patent Owner(s)

Patent OwnerAddress
STOKES BIO LIMITEDLIMERICK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aguanno, Mauro Park Central, SG 15 76
Gaughran, Mark Clare, IE 2 12
Kinahan, David Kildare, IE 6 20
Korenke, Mark Richmond, US 4 14
Lough, Matthew Westmeath, IE 2 12
Talbot, Ryan Stamford, US 4 12

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