NOVEL COMPOUND AND MEDICAL USE THEREOF

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United States of America Patent

SERIAL NO

14197381

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.

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Patent Owner(s)

Patent OwnerAddress
ONO PHARMACEUTICALS CO LTDOSAKA

International Classification(s)

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  • 2014 Application Filing Year
  • C07C Class
  • 3318 Applications Filed
  • 2843 Patents Issued To-Date
  • 85.69 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KOKUBO, Masaya Osaka, JP 25 589
YANO, Koji Osaka, JP 153 806

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Patent Citation Ranking

  • 2 Citation Count
  • C07C Class
  • 31.12 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges69512601905523531101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 70100 +010020030040050060070080090010001100120013001400

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