Peripheral Administration of Proteins Including TGF-beta Superfamily Members for Treatment of Systemic Disorders and Disease
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United States of America Patent
Stats
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N/A
Issued Date -
Jul 3, 2014
app pub date -
Jul 18, 2013
filing date -
Feb 12, 2009
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention is directed to methods and compositions for accomplishing systemic delivery of minimally-soluble bioactive agents such as, but not limited to, proteins of the TGF-β superfamily via a peripheral mode of administration. According to the invention, an exemplary bioactive agent is BMP-7. The invention further provides for minimally-invasive systemic treatment of skeletal disorders such as osteoporosis as well as minimally-invasive systemic treatment of injured or diseased non-mineralized tissues and organs such kidneys. Practice of the invention eliminates adverse side effects at the peripheral site of intravenous administration of the bioactive agent.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
STRYKER CORPORATION | PORTAGE MI |
International Classification(s)

- 2013 Application Filing Year
- A61K Class
- 12711 Applications Filed
- 11051 Patents Issued To-Date
- 86.95 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Goad, Mary Elizabeth Pecquet | Andover, US | 9 | 9 |
# of filed Patents : 9 Total Citations : 9 | |||
Haskell, Melissa M | Uxbridge, US | 5 | 8 |
# of filed Patents : 5 Total Citations : 8 | |||
Schrier, Denis | Hopkinton, US | 16 | 44 |
# of filed Patents : 16 Total Citations : 44 | |||
Wood, Susan A | Dedham, US | 17 | 839 |
# of filed Patents : 17 Total Citations : 839 |
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Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 11 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jan 3, 2026 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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