Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt

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United States of America Patent

SERIAL NO

13951152

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the genes encoding the secreted proteins Futrin 1, 2, 3 and/or 4(=R-Spondin 2, 3, 1 and 4, respectively), e.g. in connection with tumors or diseases of the muscle, kidneys or bones. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Futrin 1, 2, 3 and/or 4 or (b) the activity of the Futrin 1, 2, 3 and/or 4 protein.

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DEUTSCHES KREBSFORSCHUNGSZENTRUM69120 HEIDELBERG

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  • 2013 Application Filing Year
  • C07K Class
  • 3861 Applications Filed
  • 3209 Patents Issued To-Date
  • 83.12 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Glinka, Andrey Edingen-Neckarhausen, DE 9 34
Kazanskaya, Olga Heidelberg, DE 14 63
Niehrs, Christof Heidelberg, DE 27 181
Wu, Wei Beijing, CN 1105 10307

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges417897152521920105212101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750800850900950

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