COMPOSITIONS AND METHODS FOR TREATING DISEASES OF PROTEIN AGGREGATION INVOLVING IC3B DEPOSITION

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United States of America Patent

APP PUB NO 20140186371A1
SERIAL NO

14110137

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Abstract

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The invention provides antibodies that preferentially bind to iC3b relative to C3b. These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of diseases associated with deposits of the fragment.

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Patent Owner(s)

Patent OwnerAddress
PROTHENA BIOSCIENCES LIMITEDADELPHI PLAZA UPPER GEORGE STREET DÚN LAOGHAIRE CO DUBLIN A96 T927 IRELAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbour, Robin Walnut Creek, US 73 603
Basi, Guriqbal S Palo Alto, US 13 62

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