METHODS FOR IDENTIFYING INFLAMMATORY BOWEL DISEASE PATIENTS WITH DYSPLASIA OR CANCER
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United States of America Patent
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app pub date -
Dec 10, 2013
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Jun 14, 2011
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Abstract
The present invention provides methods for identifying IBD patients with dysplasia or cancer. In particular embodiments, the methods of the invention may comprise determining the presence or level of at least one or a panel of miRNAs in a sample obtained from an IBD patient to establish a miRNA expression profile, and comparing the miRNA expression profile with one or more pre-established model miRNA expression profiles. The present invention further provides methods for monitoring the efficacy of treatment of IBD patients with dysplasia or cancer.
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