COMPOSITIONS AND METHODS FOR TARGETING TYPE 1 INTERFERON PRODUCING CELLS
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United States of America Patent
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Issued Date -
Jun 26, 2014
app pub date -
Aug 14, 2013
filing date -
Feb 18, 2009
priority date (Note) -
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Abstract
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.
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