VARIANTS OF THE TNF SUPERFAMILY AND USES THEREOF

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United States of America Patent

APP PUB NO 20140178329A1
SERIAL NO

14105392

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Described are novel variants of APRIL that modulate signaling via receptor-specific agonist activity, and nucleic acids encoding these variant proteins. Further described is the use of these novel proteins in the treatment of APRIL-associated disorders, in particular, pathologies of the immune system and oncological disorders.

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Patent Owner(s)

Patent OwnerAddress
FUNDACIO PRIVADA CENTRE DE REGULACIO GENOMICA (CRG)DOCTOR AIGUADER 88 BARCELONA E-08003

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kimberley, Fiona Clare Teddington, GB 5 67
Medema, Jan Paul Amsterdam, NL 14 151
Pubul, Luis Serrano Barcelona, ES 1 1
Van, Der Sloot Albert Martinus Montreal, CA 4 20

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