CANCER PROGRESSION OBSERVATION INDEX GENE GROUP AND METHOD OF DETECTING THE GENE GROUP

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United States of America Patent

SERIAL NO

14239247

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Abstract

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Provided are a cancer progression observation index gene group and a method of detecting the gene group. The gene group includes cancer progression observation index genes increased or decreased when high- or low-dose radiation is performed on a mouse in which an oncogene is inserted into a thymocyte, for example, Itgb3 and Igf1 increased due to low-dose radiation to suppress the conversion of the thymocyte into a cancer cell, and Itga4, Itgb1, Itgav, Itga6, Itgb4, Raf, Myc, Fos, Trp53 and Apaf1 decreased due to high-dose radiation to stimulate the conversion of the thymocyte into a cancer cell. The gene group and the method may be used to clearly define a cancer progression observation index specifically responding to radiation.

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Patent Owner(s)

Patent OwnerAddress
KOREA HYDRO & NUCLEAR POWER CO LTD1655 BULGUK-RO YANGBUK-MYEON GYEONGJU-SI GYEONGSANGBUK-DO 38120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Seung Jin Seoul, KR 41 113
Kim, Hee Sun Seoul, KR 33 155
Shin, Seok Chul Seoul, KR 2 0

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