METHODS FOR GENERATION OF ANTIBODIES
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United States of America Patent
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Issued Date -
Jun 12, 2014
app pub date -
Sep 4, 2013
filing date -
Mar 13, 2007
priority date (Note) -
Abandoned
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Abstract
This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the efficient production of antibodies specific for antigens that are normally subject to immunological constraints such as self tolerance. The invention further relates to the production of antibody producing cells and antibodies without the need for the conventional fusing of antibody producing B cells with a myeloma fusion partner.
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