Arsenical Fluorescent Agents and Assays
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United States of America Patent
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Issued Date -
Jun 12, 2014
app pub date -
Feb 14, 2014
filing date -
Mar 19, 2010
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Abandoned
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Abstract
The invention provides methods and compositions for labeling dithiol-containing analytes, including a substituted, optionally hydro-, optionally hetero-, monoarsenical anthracene compound comprising a 4′ rotation blocking group and a 5′ arsenic, and that exhibits a detectable increase or shift in fluorescence when the arsenic reacts with two thiols of a rotation-blocking binding target molecule.
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