Use of Aptamers in Liquid Chromatography and Liquid Chromatography - Mass Spectrometry
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United States of America Patent
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Issued Date -
Jun 12, 2014
app pub date -
Dec 10, 2013
filing date -
Dec 10, 2012
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Abandoned
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Abstract
The present disclosure relates to the use of aptamers in solid phase extraction, chromatography and chromatography-mass spectrometry systems. More specifically, the present disclosure relates to the use of aptamers in SPE and chromatography systems to selectively retain, extract and/or pre-concentrate target molecule(s) having a specific affinity for the particular aptamer(s). The target molecule(s) can be further analyzed by mass spectrometry with limited interferences and/or enhanced sensitivity.
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