INHIBITORS OF EYA2

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United States of America Patent

APP PUB NO 20140155420A1
SERIAL NO

13978820

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides small molecule inhibitors of EYA2 phosphatase activity and EYA2 binding to Six1. These inhibitors are proposed for use in methods of treating cancer in a subject, such as those involving Six1 and/or EYA2 disregulation. In some embodiments, the invention further provides for the administration of a second cancer therapy to the subject.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESOFFICE OF TECHNOLOGY TRANSFER NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE SUITE 700 MSC 7788 BETHESDA MD 20892-7788

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dehdashti, Seameen Poolesville, US 1 0
Englund, Erika Washington, US 1 0
Ferrer, Marc Potomac, US 22 32
Ford, Heide L Denver, US 5 92
Marugan, Juan Gaithersburg, US 12 27
Patnaik, Samarjit Gaithersburg, US 14 52
Southall, Noel Potomac, US 10 58
Zhao, Rui Denver, US 195 1232
Zheng, Wei Potomac, US 347 2642

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