TUMOUR CELL AND TISSUE CULTURE
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United States of America Patent
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Issued Date -
Jun 5, 2014
app pub date -
Jan 6, 2012
filing date -
Jan 6, 2011
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Abstract
The present invention relates to in vitro three-dimensional organotypic cell co-culture. Cultures of the invention comprise tumour cells three-dimensionally disposed within a matrix of matrix cells which are distinct from the tumour cells, wherein the co-culture does not comprise a basement membrane. The cultures are useful for the study of cancers, for testing anti-tumour agent efficacy, and for high-throughput screening of candidate drugs.
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