INHIBITION OF FACTOR B, THE ALTERNATIVE COMPLEMENT PATHWAY AND METHODS RELATED THERETO

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United States of America Patent

APP PUB NO 20140154307A1
SERIAL NO

14183213

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Abstract

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Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL JEWISH HEALTH1400 JACKSON ST DENVER CO 80206

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gelfand, Erwin W Englewood, US 30 325
Gilkeson, Gary Steven Charleston, US 3 120
HOLERS, V Michael Denver, US 32 322
Taube, Christian Frankfurt, DE 5 135
Thurman, Joshua M Greenwood Village, US 17 264

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