TARGETED NANOVECTORS AND THEIR USE FOR TREATMENT OF BRAIN TUMORS
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United States of America Patent
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Issued Date -
Jun 5, 2014
app pub date -
Apr 26, 2012
filing date -
Apr 26, 2011
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Abandoned
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Abstract
In some embodiments, the invention pertains to therapeutic compositions for treating a brain tumor. Such therapeutic compositions generally comprise: (1) a nanovector; (2) an active agent associated with the nanovector with activity against brain tumor cells; and (3) a targeting agent associated with the nanovector with recognition activity for a marker of the brain tumor cells. In some embodiments, the active agent and the targeting agent are non-covalently associated with the nanovector. Additional embodiments of the present invention pertain to methods of treating a brain tumor in a subject (e.g., a human being) by administering the aforementioned therapeutic compositions to the subject. Further embodiments of the present disclosure pertain to methods of formulating therapeutic compositions for treating a brain tumor in a subject in a personalized manner.
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