Intestinal Permeability Assay for Neurodegenerative Diseases
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United States of America Patent
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Issued Date -
May 29, 2014
app pub date -
Nov 25, 2013
filing date -
Nov 29, 2012
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Abandoned
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Abstract
A method of identifying a subject at risk of developing or having a neurodegenerative disorder is provided. The method includes obtaining a biological sample from the subject and assaying a level of a marker of intestinal permeability in the sample. The method further includes comparing the subject's level to a control level for the marker of intestinal integrity and identifying the subject having an increased intestinal permeability relative to the control intestinal permeability as having an increased risk of developing or having a neurodegenerative disorder. A method of monitoring the efficacy of a treatment for a neurodegenerative disorder is also provided.
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