Fused Substituted Aminopyrrolidine Derivative

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United States of America Patent

SERIAL NO

14084485

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Abstract

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A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

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Patent Owner(s)

Patent OwnerAddress
DAIICHI SANKYO COMPANY LIMITED3-5-1 NIHONBASHI HONCHO CHUO-KU TOKYO 1038426 ?1038426

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Inagaki, Hiroaki Tokyo, JP 17 36
Kitamura, Takahiro Tokyo, JP 42 234
Komoriya, Satoshi Tokyo, JP 26 233
Miyauchi, Rie Tokyo, JP 27 104
Nagamochi, Masatoshi Tokyo, JP 21 185
Nakayama, Kiyoshi Tokyo, JP 71 687
Odagiri, Takashi Tokyo, JP 13 94
Takahashi, Hisashi Tokyo, JP 135 925
Takemura, Makoto Tokyo, JP 111 1114
Tsuda, Toshifumi Tokyo, JP 5 6
Yoshida, Kenichi Tokyo, JP 202 2251

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