GENERATION OF ANTIGEN SPECIFIC T CELLS
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United States of America Patent
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app pub date -
Jul 12, 2013
filing date -
Aug 5, 2005
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Abstract
The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires.
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