PROCESS FOR PREPARING SOLID AMORPHOUS PARTICLES COMPRISING TIOTROPIUM BROMIDE AND A CO-SOLID
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United States of America Patent
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Issued Date -
May 8, 2014
app pub date -
Jan 9, 2014
filing date -
Aug 16, 2007
priority date (Note) -
Abandoned
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Abstract
A method of making an inhalable medicament is provided, in particular a new solid-state form of tiotropium bromide. The medicament can be in the form of solid amorphous particles containing an intimate admixture of tiotropium bromide together with a pharmaceutically acceptable co-solid having a glass transition temperature of at least −50.degree. C., such as a sugar and/or sugar alcohol.
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