IMMUNOAFFINITY SEPARATION MATERIALS COMPRISING ANTI-IgE ANTIBODY DERIVATIVES
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United States of America Patent
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Issued Date -
May 8, 2014
app pub date -
Apr 13, 2012
filing date -
Apr 13, 2011
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Abstract
The present invention provides an immunoaffinity separation material, comprising an antibody derivative having high specificity for soluble and cell bound IgE, an apheresis device comprising said material and its use for apheresis, specifically for plasmapheresis. It further provides a recombinant single chain antibody fragment with high specificity for soluble and cell bound IgE that is free of any tag sequences as well as the method for its production.
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