TRUNCATED VARIANT OF THE MAMMALIAN TARGET FOR RAPAMYCIN (mTOR) PROTEIN

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United States of America Patent

SERIAL NO

14035634

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Abstract

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The invention relates to mTORbeta, a splice form of mTOR, nucleic acids encoding mTOR beta, and antibodies against mTOR beta. The invention also relates to methods of producing mTOR beta and methods of screening for an agent that modulates mTOR beta expression and/or activity. The invention further relates to a method of treating a disease associated with aberrant expression of mTOR beta by administration of an agent that alters mTOR activity and/or expression.

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Patent Owner(s)

Patent OwnerAddress
LUDWIG INSTITUTE FOR CANCER RESEARCH605 THIRD AVENUE NEW YORK NY 10158

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gout, Ivan London, GB 16 153
Nemazanyy, Ivan London, GB 3 0
Panasyuk, Ganna London, GB 4 0
Waterfield, Michael London, GB 22 174
Zhyvoloup, Alexander Slough, GB 3 0

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