COMBINATION MEDICINE FOR TREATMENT OF DEPRESSION

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20140107104A1
SERIAL NO

14006172

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides a combination medicine for treatment of depression, comprising a combination of (A1) an antidepressant and either (B1) a dopamine D1 receptor agonist or (C1) a dopamine D1 receptor antagonist; and a method for screening for an antidepressant that in combination with a dopamine D1 receptor agonist provides an improvement in treatment of depression, the method comprising the steps of: administering, to a mammal, (A2) a compound having an antidepressant action and (B1) a dopamine D1 receptor agonist, and detecting a greater increase in depression-related gene expression, dopamine D1 receptor expression and/or dopamine D1 receptor signaling in comparison with the case where (A2) the compound having an antidepressant action or (B1) the dopamine D1 receptor agonist is administered.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
THE ROCKEFELLER UNIVERSITY1230 YORK AVENUE NEW YORK NY 10065
KURUME UNIVERSITYFUKUOKA
NIPPON MEDICAL SCHOOL FOUNDATION1-1-5 SENDAGI BUNKYO-KU TOKYO 113-8602
SCHOOL JURIDICAL PERSON FUJITA EDUCATIONAL INSTITUTION12-1 MINAMIYAKATA SAKAE-CHO TOYOAKE-SHI AICHI 470-1168

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greengard, Paul New York, US 40 643
Kobayashi, Katsunori Tokyo, JP 26 187
Miyakawa, Tsuyoshi Aichi, JP 4 30
Nishi, Akinori Fukuoka, JP 6 95

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation