Edible composition

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United States of America Patent

PATENT NO 9387219
APP PUB NO 20140107052A1
SERIAL NO

14122355

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Foods or meals high in available carbohydrate such as sucrose or starch increase post-prandial blood glucose concentrations. Repeated high post-prandial plasma glucose “spikes” are associated with an increased risk of developing type II diabetes. Unregulated glycemic excursions are undesirable, and any reduction or “blunting” of the post-prandial glucose concentration in blood is potentially beneficial. This invention relates to an edible composition for delay of intestinal glucose uptake through synergistic inhibition of both active sodium glucose co-transporter 1 (SGLT1) and passive glucose transporter 2 (GLUT2) leading to flattening or blunting of the post-prandial glucose peak. Thus in a first aspect of the invention, an edible composition is provided, the composition comprising at least 5% dry weight at least one flavonoid aglycone and at least 5% dry weight at least one flavonoid glucoside, wherein the flavonoid glucoside is at least 20%, preferably at least 40%, most preferably at least 60% more resistant to hydrolysis by lactase phloridzin hydrolase than quercetin-4-glucoside, and wherein the flavonoid aglycone is a GLUT 2 inhibitor and the flavonoid glucoside is a SGLT 1 inhibitor.

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Patent Owner(s)

Patent OwnerAddress
CONOPCO INC D/B/A UNILEVER700 SYLVAN AVENUE (A4) ENGLEWOOD CLIFFS NJ 07632

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berry, Mark John Sharnbrook, GB 28 175
Fowler, Mark Ian Sharnbrook, GB 6 1
Heath, Alan David Sharnbrook, GB 3 8

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