METHOD FOR PRODUCING YEAST EXPRESSED HPV TYPES 6 AND 16 CAPSID PROTEINS

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United States of America Patent

APP PUB NO 20140099719A1
SERIAL NO

13893821

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Abstract

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Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS VACCINES AND DIAGNOSTICS INCEMERYVILLE CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bensi, Giuliano Firenze, IT 21 127
Buonamassa, Daniela Tornese Siena, IT 5 14
Galeotti, Cesira L Montegriggioni, IT 6 23
Greer, Catherine E Oakland, US 10 326
Petracca, Roberto Siena, IT 11 14

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