NITRIC OXIDE/cGMP PATHWAY INHIBITION OF VLA-4 RELATED CELL ADHESION

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United States of America Patent

APP PUB NO 20140088034A1
SERIAL NO

14115170

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Abstract

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The invention provides methods of treating nitric oxide/cGMP pathway-cell adhesion disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention relates to a method for down-regulating α4β1-integrin affinity and inhibiting and reversing adhesion formation in patients or subjects in need using a nitric oxide donor.

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Patent Owner(s)

Patent OwnerAddress
STC UNM801 UNIVERSITY BLVD SE SUITE 101 ALBUQUERQUE NM 87106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chigaev, Alexandre Santa Fe, US 6 7
Sklar, Larry A Albuquerque, US 58 580

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