COMPOSITIONS AND METHODS FOR DETECTING ABERRANT REGULATION, EXPRESSION, AND LEVELS OF HGH

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United States of America Patent

APP PUB NO 20140087964A1
SERIAL NO

14035422

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Abstract

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Detection of human growth hormone use is very challenging due to the short half-life of circulating human growth hormone and the fact that the recombinant human growth hormone used is identical in protein sequence as the native, naturally produced growth hormone. The chief objective of this invention is to discover a marker(s) that will identify use of recombinant human growth hormone use. In the case of this invention, we have discovered specific circulating micro RNA (miRNA) that can be detected and quantified in plasma of individuals taking recombinant human growth hormone.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF VIRGINIA PATENT FOUNDATIONCHARLOTTESVILLE VA 22903

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bruns, David E Greenwood, US 2 14
Haverstick, Doris M Charlottesville, US 7 9
Kelly, Brian N Holladay, US 1 0

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