NEAR-INFRARED SILVER SULFIDE QUANTUM DOT, PREPARATION METHOD THEREFOR AND BIOLOGICAL APPLICATION THEREOF
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United States of America Patent
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Issued Date -
Mar 27, 2014
app pub date -
Feb 10, 2012
filing date -
May 30, 2011
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Abandoned
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Abstract
Provided are near-infrared silver sulfide quantum dots, a preparation method thereof and a biological application thereof. The silver sulfide quantum dots have hydrophilic groups derived from a mercapto-containing hydrophilic reagent attached on the surface thereof, and the hydrophilic reagent is any one of mercaptoacetic acid, mercaptopropionic acid, cysteine, cysteamine, thioctic acid and ammonium mercaptoacetate or any combination thereof. The silver sulfide quantum dots have high fluorescence yield, good fluorescence stability, good biocompatibility and uniform sizes. The preparation method has moderate reaction conditions, simple operation, short production cycle, good reproducibility and is easy to control. The silver sulfide quantum dots can be used in the application of cellular imaging and biological tissue imaging.
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