ARYL AMINE SUBSTITUTED PYRIMIDINE AND QUINAZOLINE AND THEIR USE AS ANTICANER DRUGS

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United States of America Patent

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14026545

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A series of mono- and di-substituted quinazoline and pyrimidine derivatives based on the skeleton of erlotinib (an EGFR inhibitor) were synthesized and their bioactivities against hepatocellular carcinoma and human lung adenocarcinoma were evaluated.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL YANG-MING UNIVERSITYTAIPEI 112
NATIONAL TAIWAN UNVERSITYNO 1 SEC 4 ROOSEVELT ROAD TAIPEI 10617

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Kuen-Feng Taipei, TW 8 22
SHIAU, Chung-Wai Taipei, TW 14 50

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