PSA ASSAY AND REAGENT THEREFOR
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United States of America Patent
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Issued Date -
Mar 20, 2014
app pub date -
Mar 28, 2012
filing date -
Mar 28, 2011
priority date (Note) -
Abandoned
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Abstract
Provided is a method for the simple and highly accurate assay of PSA by a one-step reaction that does not use carriers having different average grain sizes. Also provided is a reagent therefor. The PSA assay method comprises sensitizing insoluble carriers having the same average grain size within a range of greater than 0.20 μm but 0.40 μm or less using two types of anti-PSA monoclonal antibodies having different epitopes that are anti-PSA monoclonal antibodies that will react with both free PSA and PSA-ACT, which is a complex of free PSA and α1-antichymotrypsin, and bringing the carriers into contact with a sample in the presence of an aggregation promoter.
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