MODULATION OF GRANULOSA CELL APOPTOSIS
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United States of America Patent
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app pub date -
Aug 15, 2013
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Jul 18, 2005
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Abstract
The present invention relates to a method of modulating apoptosis of a granulosa cell. The method includes one or more of the following steps: (i) modulating the concentration and/or activity of BMP-15 and/or BMP-6 that the granulosa cell is exposed to; (ii) modulating activity of a BMP-15 dependent signalling pathway in the granulosa cell; and (iii) modulating activity of a BMP-6 dependent signalling pathway in a granulosa cell.
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