Water-Free Pharmaceutical Compositions Suitable for Local Anaesthetics
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United States of America Patent
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Issued Date -
Mar 6, 2014
app pub date -
Mar 30, 2011
filing date -
Apr 1, 2010
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a water-free pharmaceutical composition comprising one or more local anaesthetics in base form and which is suitable for topical administration. The composition further comprises a lipid vehicle comprising long-chain triglycerides (LCT) and at least 10% by weight of medium-chain monoglycerides (MCM) selected so the composition has an at least semi-solid appearance at the body temperature at the site of administration. The invention further relates to methods of producing and sterilizing the compositions.
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