TEST SYSTEMS AND METHODS FOR IDENTIFYING AND CHARACTERISING LIPID LOWERING DRUGS
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United States of America Patent
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Mar 6, 2014
app pub date -
Apr 30, 2012
filing date -
Apr 29, 2011
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Abstract
The present invention relates to methods for the identification and characterization of therapeutic candidates for use in the treatment of a disease or condition associated with elevated LDL-C levels involving a rodent, methods for the testing of the efficacy of an antibody specifically binding to proprotein convertase subtilisin/kexin type 9 (PCSK9) involving a rodent, as well as a rodent and its use in the identification or profiling of compounds for modulation of a disease or condition associated with elevated LDL-C levels.
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