WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF

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United States of America Patent

SERIAL NO

14070948

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Abstract

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The invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.

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Patent Owner(s)

Patent OwnerAddress
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITYSUITA-SHI OSAKA 565-0871

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ISHIKAWA, Toyokazu Kanonji-shi, JP 6 9
KOJIMA, Asato Tokyo, JP 3 34
TAKAHASHI, Hidehiro Tokyo, JP 9 143

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