Materials and Methods Relating to Cardiovascular Imaging
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United States of America Patent
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Issued Date -
Mar 6, 2014
app pub date -
Feb 8, 2012
filing date -
Feb 8, 2011
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Abandoned
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Abstract
The invention provides conjugates for imaging plaques, such as cardiovascular plaques, as well as associated pharmaceutical compositions. Other aspects of the invention include methods for administering and imaging such conjugates and compositions, and using the imaging to characterise plaques. The conjugates of the invention distinguish between tropoelastin and elastin in plaques. The presence of tropoelastin can act as an indication that a plaque is liable to rupture or erode. Such information allows assessment of disease progression and response to treatment.
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