USE OF NITROGEN GAS IN THAWING PLATES IN A LiN-BASED LYOPHILIZATION UNIT
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United States of America Patent
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Issued Date -
Mar 6, 2014
app pub date -
Aug 31, 2012
filing date -
Aug 31, 2012
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This work is in simplifying the freezing and heating process required for a typical lyophilization process. From a liquid nitrogen supply tank called LIN tank, calculated quantity of vaporized nitrogen is transported the use point where a heater that uses heating media heats up nitrogen to a desired temperature and pass into the annular space of the steel plate where lyophilized solvent such as water of solvent is deposited on the outer surface of the plate. The heated nitrogen temperature will dictate the rate at which the solvent or water will be thawed. This unique process offer simplicity, safety and ease operation allowing the user to avoid heating oil as heating media, a common practice in the industry.
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