PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CANCER COMPRISING STIGMASTEROL AND 5 BETA-HYDROXYSITOSTANOL ISOLATED FROM NAVICULA INCERTA
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United States of America Patent
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Issued Date -
Feb 27, 2014
app pub date -
Oct 31, 2012
filing date -
Aug 23, 2012
priority date (Note) -
Abandoned
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Abstract
A novel use of phytosterol isolated from Navicula incerta having effect of preventing or treating liver cancer is provided. Accordingly, a composition for preventing or treating liver cancer including stigmasterol and 5β-hydroxysitostanol isolated from Navicula incerta as an active ingredient is provided. Accordingly, and 5β-hydroxysitostano upregulate expression of genes involved with hepatoma cell apoptosis inducing factors, while downregulating genes involved with hepatoma cell apoptosis inhibiting genes, thereby lead into effective prevention or treatment of liver cancer.
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