ANTCIN DERIVATIVES IN COMBINATION WITH ANTI-CANCER DRUGS IN THE TREATMENT AND/OR PREVENTION OF TUMORS
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United States of America Patent
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Feb 27, 2014
app pub date -
Aug 23, 2013
filing date -
Aug 24, 2012
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Abstract
The invention surprisingly found that antcin or an ester derivative, salt or a composition thereof in combination with an anti-tumor drug provides unexpected efficacy in inhibiting tumors, while retaining normal cells at high viability. In addition, the amount of the anti-tumor drug in chemotherapy can be reduced by combinatorially using antcin or an ester derivative, salt or a composition thereof in view of the fact that they play a role in adjuvant therapy.
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