HUMAN INSULIN AND ANALOG CONJUGATE THEREOF
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United States of America Patent
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Issued Date -
Feb 27, 2014
app pub date -
Mar 19, 2012
filing date -
Mar 17, 2011
priority date (Note) -
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Abstract
Disclosed is a recombinant human insulin or analog conjugate thereof. Said conjugate is formed by connecting the ε-amino group of lysine 29 of the B chain to activated polyethylene glycol by means of an amide bond. Further disclosed is a method of preparing said conjugate, a pharmaceutical compound, and a use for said conjugate in preparing medication for treating Type 1 and Type 2 diabetes.
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