PEPTIDE WHICH CAN INDUCE ANTIBODY CAPABLE OF RECOGNIZING STEREOSTRUCTURE OF HIV
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United States of America Patent
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Issued Date -
Feb 27, 2014
app pub date -
Apr 3, 2012
filing date -
Apr 4, 2011
priority date (Note) -
Abandoned
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Abstract
An object of the present invention is to provide a peptide capable of inducing a superior or new neutralizing antibody against HIV, so that HIV infectious disease can be prevented and treated or a greater variety of preventive or therapeutic options can be offered. This object is achieved by using a peptide inducing an HIV's three-dimensional structure-recognizing antibody that recognizes a trimer region of C34, wherein three molecules of a derivative of a helical region C34 peptide at C-terminal region of transmembrane protein gp41 of an HIV particle are ligated via a C3-symmetric template compound having three equivalent linker structures.
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