METHOD AND KIT FOR THE DETECTION OF GENES ASSOCIATED WITH PIK3CA MUTATION AND INVOLVED IN PI3K/AKT PATHWAY ACTIVATION IN THE ER-POSTITIVE AND HER2-POSITIVE SUBTYPES WITH CLINICAL IMPLICATIONS

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United States of America Patent

APP PUB NO 20140056881A1
SERIAL NO

14032984

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Abstract

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A method to determine the clinical outcome of breast tumour affecting a patient if treated with an antitumoural agent against breast tumour, the said method comprising the step of assaying a sample of a breast tumour from said patient for an expression level of selected genes, by contacting mRNA sequences from the cells of this breast tumour with a set of more than 3 nucleotide sequences related to human mutated PIK3CA.

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UNIVERSITE LIBRE DE BRUXELLESBRUSSELS BELGIUM BRUSSELS BRUSSELS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HAIBE-KAINS, Benjamin Bruxelles, BE 5 1
LOI, Sherene Brussels, BE 3 1
McARTHUR, Grant Camberwell, AU 4 355
SOTIRIOU, Christos Uccle, BE 9 27

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