METHOD FOR THE PRODUCTION OF RECOMBINANT HUMAN FACTOR VIII
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United States of America Patent
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Issued Date -
Feb 20, 2014
app pub date -
Mar 11, 2011
filing date -
Mar 11, 2011
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Abstract
The object of the present invention is to provide methods for the production of recombinant human Factor VIII, employing specific endoproteases, thus assuring full proteolytic processing of said factor even during its biosynthesis, consequently avoiding additional purification steps. Other objects of the present invention are the recombinant human Factor VIII as obtained by said methods, pharmaceutical compositions, related uses and therapeutic methods.
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