Phosphonate Ester Derivatives and Methods of Synthesis Thereof

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United States of America Patent

SERIAL NO

14057391

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Abstract

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The disclosure describes methods of synthesis of phosphonate ester derivatives. Preferred methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of phosphonate ester derivatives without the use of chromatographic purification methods and in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of phosphonate ester derivatives.

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CHIMERIX INC2505 MERIDIAN PARKWAY SUITE 100 DURHAM NC 27713

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Almond, Merrick R Apex, US 22 321
Lampert, Bernhard M Rougemont, US 3 48
Ware, Roy W Raleigh, US 16 108

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