Single Nucleotide Polymorphism Biomarkers for Diagnosing Autism
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United States of America Patent
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Issued Date -
Feb 13, 2014
app pub date -
Dec 9, 2011
filing date -
Dec 10, 2010
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Abstract
The invention provides methods of identifying biomarkers associated with autism or autism spectrum disorder based upon quantitative trait association analyses using genome-wide genotype data combined with case-control association analyses using distinct ASD phenotypes identified on the basis of symptomatic profiles, including deficits in language usage, non-verbal communication, social development, play skills, and insistence on sameness and rituals. Also provided are compositions identified using the methods of the invention and use thereof.
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